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Darrell R Fisher Selected Research

procaine isothiocyanate (PRIT)

12/2020Therapy of Myeloid Leukemia using Novel Bispecific Fusion Proteins Targeting CD45 and 90Y-DOTA.
1/2018CD38-bispecific antibody pretargeted radioimmunotherapy for multiple myeloma and other B-cell malignancies.
12/2017Metal-Free Cycloaddition Chemistry Driven Pretargeted Radioimmunotherapy Using α-Particle Radiation.
11/2016Comparative Analysis of Bispecific Antibody and Streptavidin-Targeted Radioimmunotherapy for B-cell Cancers.
1/2015Comparative efficacy of 177Lu and 90Y for anti-CD20 pretargeted radioimmunotherapy in murine lymphoma xenograft models.
2/2014A preclinical model of CD38-pretargeted radioimmunotherapy for plasma cell malignancies.
7/2011Anti-CD45 pretargeted radioimmunotherapy using bismuth-213: high rates of complete remission and long-term survival in a mouse myeloid leukemia xenograft model.
11/2010Conventional and pretargeted radioimmunotherapy using bismuth-213 to target and treat non-Hodgkin lymphomas expressing CD20: a preclinical model toward optimal consolidation therapy to eradicate minimal residual disease.
8/2009Pretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates.
1/2009Pretargeted radioimmunotherapy using anti-CD45 monoclonal antibodies to deliver radiation to murine hematolymphoid tissues and human myeloid leukemia.

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Darrell R Fisher Research Topics

Disease

33Neoplasms (Cancer)
04/2022 - 01/2005
11Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2021 - 01/2003
10Lymphoma (Lymphomas)
11/2022 - 01/2003
8Melanoma (Melanoma, Malignant)
02/2022 - 01/2005
7Leukemia
12/2020 - 01/2009
6Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2020 - 03/2006
4B-Cell Lymphoma (Lymphoma, B Cell)
11/2022 - 04/2007
4Myeloid Leukemia (Leukemia, Myelocytic)
12/2020 - 01/2009
4Hematologic Neoplasms (Hematological Malignancy)
01/2020 - 01/2005
3Multiple Myeloma
01/2021 - 02/2014
2AIDS-Related Complex (ARC)
01/2021 - 12/2019
2Hodgkin Disease (Hodgkin's Disease)
01/2021 - 12/2019
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
09/2014 - 12/2009
2Neoplasm Metastasis (Metastasis)
10/2006 - 10/2005
1Edema (Dropsy)
01/2022
1Pain (Aches)
01/2022
1Hypesthesia (Numbness)
01/2022
1Inflammation (Inflammations)
01/2022
1Osteosarcoma (Osteogenic Sarcoma)
12/2021
1Plasma Cell Leukemia
01/2021
1Experimental Melanoma
07/2019
1Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2016
1Burkitt Lymphoma (Burkitt's Lymphoma)
01/2015
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
01/2015
1Peritoneal Neoplasms
10/2014
1Cardiomyopathies (Cardiomyopathy)
09/2014
1Plasmacytoma
02/2014
1Residual Neoplasm
11/2010
1Prostatic Neoplasms (Prostate Cancer)
10/2006
1Body Weight (Weight, Body)
10/2006

Drug/Important Bio-Agent (IBA)

18Radioisotopes (Radionuclides)IBA
04/2022 - 01/2003
10procaine isothiocyanate (PRIT)IBA
12/2020 - 01/2009
81,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA
02/2022 - 01/2003
7Peptides (Polypeptides)IBA
02/2022 - 01/2005
5Proteins (Proteins, Gene)FDA Link
12/2020 - 04/2005
5Monoclonal AntibodiesIBA
01/2020 - 01/2009
5Biotin (Vitamin H)FDA Link
01/2018 - 11/2010
5StreptavidinIBA
11/2016 - 04/2005
4alpha-MSHIBA
02/2022 - 01/2005
4AcidsIBA
02/2022 - 04/2005
4RadiopharmaceuticalsIBA
01/2022 - 08/2005
4fludarabineIBA
01/2021 - 12/2009
4DOTA-biotin (90Y-DOTA-biotin)IBA
12/2020 - 04/2005
3Type 1 Melanocortin ReceptorIBA
02/2022 - 01/2019
3YttriumIBA
01/2021 - 01/2003
3Indicators and Reagents (Reagents)IBA
07/2019 - 10/2005
2Yttrium-90IBA
01/2021 - 01/2021
2Phosphates (Orthophosphate)IBA
01/2021 - 05/2008
2Etoposide (VP 16)FDA LinkGeneric
01/2021 - 01/2020
2SolutionsIBA
01/2021 - 02/2020
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2020 - 03/2006
2AntigensIBA
12/2019 - 01/2009
2Iodine-131IBA
12/2019 - 09/2014
2LactamsIBA
11/2019 - 01/2019
2AntibodiesIBA
07/2019 - 04/2008
1AlbuminsIBA
02/2022
1Cytarabine (Cytosar-U)FDA LinkGeneric
01/2021
1Carmustine (FIVB)FDA Link
01/2021
1HydrogelsIBA
01/2021
1Melphalan (Alkeran)FDA LinkGeneric
01/2021
1PolymersIBA
01/2021
1Melanocyte-Stimulating Hormones (MSH)IBA
11/2019
1Melanins (Melanin)IBA
07/2019
1Immunoglobulin G (IgG)IBA
07/2019
1LigandsIBA
12/2017
1venetoclaxIBA
01/2017
1Cesium-137IBA
01/2017
1Oncogene Proteins (Oncogene Protein)IBA
01/2016
1Rhenium-188IBA
01/2016
1Lutetium-177IBA
01/2016
1Immunoconjugates (Immunoconjugate)IBA
10/2014
1ErbB Receptors (EGF Receptor)IBA
10/2014
1Trastuzumab (Herceptin)FDA Link
10/2014
1ADP-ribosyl Cyclase 1IBA
02/2014
1tositumomab I-131 (Bexxar)FDA Link
12/2012
1Radium-223IBA
07/2012
1BismuthIBA
07/2011
1Bismuth-213IBA
11/2010
1Leukocyte Common Antigens (CD45 Antigen)IBA
01/2009
1ApoferritinsIBA
05/2008
1Hormones (Hormone)IBA
10/2006
1Glutamic Acid (Glutamate)FDA Link
08/2006
1Amino AcidsFDA Link
08/2006
1Ac- Cys- Cys- Glu- His- D- Phe- Arg- Trp- Cys- Lys- Pro- Val- NH2IBA
08/2006
1Liposomes (Liposome)IBA
07/2006

Therapy/Procedure

22Radioimmunotherapy
11/2022 - 01/2003
22Therapeutics
04/2022 - 07/2002
8Cell Transplantation
11/2022 - 01/2005
4Injections
01/2021 - 10/2006
4Radiotherapy
01/2017 - 10/2006
3Drug Therapy (Chemotherapy)
01/2021 - 05/2013
2Homologous Transplantation
11/2022 - 09/2014
2Immunotherapy
01/2021 - 07/2019
2Transplantation
09/2014 - 06/2014
2Stem Cell Transplantation
06/2014 - 04/2007
2Hematopoietic Stem Cell Transplantation
05/2013 - 04/2007
1Euthanasia (Mercy Killing)
12/2020
1Autologous Transplantation
01/2020
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
05/2013
1Gamma Cameras (Gamma Camera)
04/2009